Estrogen receptor acting in cis enhances WT and mutant p53 t…
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- DOI 10.1073/pnas.0909129107
- PMID https://pubmed.ncbi.nlm.nih.gov/20080630
- OpenAlex ID W2035435589
- Type Article
- Language EN
- Published 04 Jan 2010
- Volume 107 (4)
- Pages 1500–1505
- Source Proceedings of the National Academy of S…
- Publisher National Academy of Sciences
- FWCI 3.00
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 01 Oct 2026
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Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences
Article 2010 EN Green
p53 is a master regulatory, sequence-specific transcription factor that directly controls expression of over 100 genes in response to various stress signals. Transactivation is generally considered to occur through p53 binding to a consensus response element (RE) composed of two 5'-RRRCWWGYYY-3' decamers. Recently, studying the human angiogenesis-related gene FLT1 we discovered that p53 can mediat…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Daniel Menéndez | National Institutes of Health (US) National Institute of Environm… (US) | |
| 2 | Alberto Inga | — | |
| 3 | Michael A. Resnick | National Institutes of Health (US) National Institute of Environm… (US) |
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