MECHANISM OF INCREASED PROLACTIN SECRETION BY SULPIRIDE

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MECHANISM OF INCREASED PROLACTIN SECRETION BY SULPIRIDE

Article 1977 EN

The effect of sulpiride, a neuroleptic agent, on the secretion of prolactin by the anterior pituitary gland of the rat was studied. A significant increase in serum prolactin was observed after subcutaneous administration of the drug. Although sulpiride (0-10 micronmol/1 or 0-14 mmol/1) had no effect on the secretion of newly synthesized or radioimmunoassayable prolactin in vitro, the drug signific…

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1 Robert M. MacLeod — —
2 Claude Robyn — —

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