Protein Kinase C Inhibition Enhances Platelet-activating Fac…

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33
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1998
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  • DOI 10.1165/ajrcmb.18.1.2817
  • PMID https://pubmed.ncbi.nlm.nih.gov/9448055
  • OpenAlex ID W2005182773
  • Type Article
  • Language EN
  • Published 01 Jan 1998
  • Volume 18 (1)
  • Pages 136–144
  • Source American Journal of Respiratory Cell and…
  • Publisher American Thoracic Society
  • FWCI 3.01
  • Countries 1
  • Institutions 1
  • Added 10 Oct 2025
  • Updated 16 Oct 2026
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Protein Kinase C Inhibition Enhances Platelet-activating Factor-induced Eicosanoid Production in Human Eosinophils

Article 1998 EN

Previous investigations have suggested that protein kinase C (PKC) may regulate guinea pig eosinophil responses through a suppressive "negative feedback" mechanism. Using the selective PKC inhibitors bisindolylmaleimide I (Bis I, GF 109203X) and calphostin C, we examined the role of PKC in platelet-activating factor (PAF)-induced respiratory burst and generation of arachidonic acid metabolites in…

33

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24

References

7

Authors

3.01

FWCI

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7 authors
#AuthorInstitutionsORCID
1 Gordon Dent Corresponding University of Chicago (US)
2 N. M. Muñoz University of Chicago (US) —
3 Elke Rühlmann University of Chicago (US) —
4 Xiangdong Zhu University of Chicago (US)
5 Alan R. Leff University of Chicago (US) —
6 HELGO MAGNUSSEN University of Chicago (US) —
7 Klaus Friedrich Rabe University of Chicago (US)
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