Conventional Knockout of Tbc1d1 in Mice Impairs Insulin- and…
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- DOI 10.1210/en.2012-2147
- PMID https://pubmed.ncbi.nlm.nih.gov/23892475
- OpenAlex ID W2003991696
- Type Article
- Language EN
- Published 27 Jul 2013
- Volume 154 (10)
- Pages 3502–3514
- Source Endocrinology
- Publisher Oxford University Press
- FWCI 3.88
- Countries 3
- Institutions 6
- Added 24 Jun 2016
- Updated 31 Oct 2026
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Conventional Knockout of Tbc1d1 in Mice Impairs Insulin- and AICAR-Stimulated Glucose Uptake in Skeletal Muscle
Article 2013 EN Hybrid
In the obesity-resistant SJL mouse strain, we previously identified a naturally occurring loss-of-function mutation in the gene for Tbc1d1. Characterization of recombinant inbred mice that carried the Tbc1d1(SJL) allele on a C57BL/6J background indicated that loss of TBC1D1 protects from obesity, presumably by increasing the use of fat as energy source. To provide direct functional evidence for an…
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7
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3.88
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
7 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Janine Dokas | German Institute of Human Nutr… (DE) | — |
| 2 | Alexandra Chadt | Deutsches Diabetes-Zentrum e.V… (DE) | |
| 3 | Tobias Nolden | Max Planck Institute for Molec… (DE) | |
| 4 | Heinz Himmelbauer | Universitat Pompeu Fabra (ES) Centre for Genomic Regulation (ES) +1 | |
| 5 | Juleen Rae Zierath | Karolinska Institutet (SE) | |
| 6 | Hans‐Georg Joost | Deutsches Diabetes-Zentrum e.V… (DE) German Institute of Human Nutr… (DE) | |
| 7 | Hadi Al‐Hasani Corresponding | Deutsches Diabetes-Zentrum e.V… (DE) |
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