Induction of interleukin-1 and tumor necrosis factor by 12-O…
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- DOI 10.1093/carcin/10.6.1107
- PMID https://pubmed.ncbi.nlm.nih.gov/2785869
- OpenAlex ID W1990666100
- Type Article
- Language EN
- Published 01 Jan 1989
- Volume 10 (6)
- Pages 1107–1111
- Source Carcinogenesis
- Publisher Oxford University Press
- FWCI 0.92
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 16 Oct 2026
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Induction of interleukin-1 and tumor necrosis factor by 12-O-tetradecanoylphorbol-13-acetate in phorbol ester-sensitive (SENCAR) and resistant (B6C3F1) mice
Article 1989 EN
12-O-tetradecanoylphorbol-13-acetate (TPA), the most potent skin tumor promoter known, evokes significant inflammatory responses in mouse skin after topical application. Infiltrating inflammatory cells have been hypothesized to contribute to genetic damage in epidermal cells through the generation of reactive oxygen intermediates (ROIs), thus facilitating the development of tumors. Interleukin-1 (…
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1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Lawrence W. Updyke | Purdue University West Lafayet… (US) | — |
| 2 | Hyunah L. Yoon | Purdue University West Lafayet… (US) | — |
| 3 | Anchalee Chuthaputti | Purdue University West Lafayet… (US) | — |
| 4 | Richard W. Pfeifer | Purdue University West Lafayet… (US) | |
| 5 | George K. W. Yim | Purdue University West Lafayet… (US) | — |
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