Enhancement of N-methyl-N'-nitro-N-nitrosoguanidine transfor…
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- DOI 10.1073/pnas.77.12.7282
- PMID https://pubmed.ncbi.nlm.nih.gov/6938975
- OpenAlex ID W1989085331
- Type Article
- Language EN
- Published 01 Dec 1980
- Volume 77 (12)
- Pages 7282–7286
- Source Proceedings of the National Academy of S…
- Publisher National Academy of Sciences
- FWCI 3.48
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 27 Oct 2026
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Enhancement of N-methyl-N'-nitro-N-nitrosoguanidine transformation of Syrian hamster cells by a phorbol diester is independent of sister chromatid exchanges and chromosome aberrations.
Article 1980 EN Green
12-O-Tetradecanoylphorbol 13-acetate (TPA), a known tumor promoter, enhances the morphologic transformation of Syrian hamster embryo cells induced by low transforming concentrations of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) (0.025-0.1 microgram/ml) without potentiation of cell lethality or of changes in sister chromatid exchanges (SCEs) or chromosomal aberration frequencies. When MNNG was add…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | N.C. Popescu | National Institutes of Health (US) National Cancer Institute (US) | — |
| 2 | Suzanne C. Amsbaugh | National Institutes of Health (US) National Cancer Institute (US) | — |
| 3 | Joseph A. DiPaolo | National Institutes of Health (US) National Cancer Institute (US) | — |
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