Increased expression of the female-predominant cytochrome P4…

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Increased expression of the female-predominant cytochrome P4502C12 in liver nodules from male Wistar rats

Article 1993 EN

Nodules and hepatomas from male and female rats treated according to the resistant hepatocyte (RH) model were analyzed with respect to expression of the male-predominant cytochrome P4502C11 (P450(16 alpha)) and the female-predominant cytochrome P4502C12 (P450(15 beta)) at the transcriptional and at the mRNA and protein levels. In male nodules isolated 8 and 11 to 12 months after initiation and in…

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6 authors
#AuthorInstitutionsORCID
1 Agneta Blanck Karolinska Institutet (SE) —
2 Inger Porsch Hällström Karolinska Institutet (SE)
3 Dan Svensson Karolinska Institutet (SE) —
4 Agneta Mode Karolinska Institutet (SE) —
5 Lennart C. Eriksson Karolinska Institutet (SE) —
6 Jan-Ακε Gustafsson Houston Methodist (US) Karolinska Institutet (SE)

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