Regulation of p63 Function by Mdm2 and MdmX
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- DOI 10.1089/10445490152122433
- PMID https://pubmed.ncbi.nlm.nih.gov/11445003
- OpenAlex ID W1970135335
- Type Article
- Language EN
- Published 01 Jun 2001
- Volume 20 (6)
- Pages 321–330
- Source DNA and Cell Biology
- Publisher Mary Ann Liebert, Inc.
- FWCI 2.17
- Countries 1
- Institutions 1
- Added 10 Oct 2025
- Updated 15 Oct 2026
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Regulation of p63 Function by Mdm2 and MdmX
Article 2001 EN
p63, a p53-related protein, has been shown to activate p53-responsive genes and induce apoptosis in certain cell types. In this study, we examined the effects of Mdm2 and MdmX proteins on p63 transactivation, apoptosis, and protein levels. The isoforms of p63 most structurally similar to p53, p63gamma (p51A) and p63alpha (p51B), were chosen for study. Our results confirm earlier reports demonstrat…
75
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41
References
3
Authors
2.17
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Madhavi Kadakia | Wright State University (US) | |
| 2 | Charlotte Slader | Wright State University (US) | — |
| 3 | Steven J. Berberich | Wright State University (US) | — |
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