Keeping It Real: Real-World Brodalumab Outcomes in the Conte…

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2026
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  • DOI 10.25251/a384hv18
  • OpenAlex ID W7211936489
  • Type Article
  • Language EN
  • Published 08 Sep 2026
  • Volume 10 (4)
  • Pages s800
  • Source SKIN The Journal of Cutaneous Medicine
  • Countries 2
  • Institutions 7
  • Added 09 Sep 2026
  • Updated 28 Oct 2026
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Keeping It Real: Real-World Brodalumab Outcomes in the Context of Pivotal Trials for Moderate-to-Severe Plaque Psoriasis

Article 2026 EN Diamond

Introduction Brodalumab is the only interleukin-17 (IL-17) receptor A blocker approved for moderate-to-severe plaque psoriasis and blocks downstream signaling of multiple IL-17 isoforms including IL-17A, IL-17F, IL-17C, IL-17E, and IL-17A/F. Here, we contextualize effectiveness and safety of brodalumab in adult patients in the Canadian Real-World Evidence (CARE) study alongside results from pivota…

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
6 authors
#AuthorInstitutionsORCID
1 Marni Wiseman University of Manitoba (CA)
2 Sunil Kalia University of British Columbia (CA)
3 Charles W Lynde University of Toronto (CA) Lynde Centre for Dermatology (CA) +1
4 David Adam University of Toronto (CA) Probity Medical Research (CA) —
5 April W. Armstrong University of California, Los … (US)
6 Mark Lebwohl Icahn School of Medicine at Mo… (US)

Data: OpenAlex