Intratumoral Mycobacterium abscessus promotes cytidine deami…
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- DOI 10.1038/s41392-026-02878-z
- PMID https://pubmed.ncbi.nlm.nih.gov/42675040
- OpenAlex ID W7204852638
- Type Article
- Language EN
- Published 31 Aug 2026
- Volume 11 (1)
- Source Signal Transduction and Targeted Therapy
- Publisher Springer Nature
- Countries 1
- Institutions 3
- Added 01 Sep 2026
- Updated 06 Oct 2026
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Intratumoral Mycobacterium abscessus promotes cytidine deaminase mutagenesis in non-small cell lung cancer
Article 2026 EN Gold
The intratumoral microbiota is increasingly recognized as an active component of the tumor microenvironment, yet whether it directly drives tumor mutagenesis remains unclear. Here, integrated multi-omics analysis of human non-small cell lung cancer (NSCLC) identifies Mycobacterium abscessus as a microbial determinant of APOBEC3A-associated mutagenesis. Mechanistically, the bacterial effector nucle…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
12 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Xun� Li | Second Affiliated Hospital of … (CN) | |
| 2 | Mei-Ting Li | Second Affiliated Hospital of … (CN) | — |
| 3 | Ke-Peng Ou | Chongqing University of Arts a… (CN) | — |
| 4 | Pan-Qi Gao | Second Affiliated Hospital of … (CN) | — |
| 5 | An-Hua Xiao | Second Affiliated Hospital of … (CN) | — |
| 6 | Ji Yang | Second Affiliated Hospital of … (CN) | |
| 7 | Jia-Ning Li | Second Affiliated Hospital of … (CN) | — |
| 8 | Wanyan Deng | Second Affiliated Hospital of … (CN) | |
| 9 | Meng-jun Bie Corresponding | The Affiliated Yongchuan Hospi… (CN) | — |
| 10 | Ailong Huang Corresponding | Second Affiliated Hospital of … (CN) | |
| 11 | Xiaofeng Shi Corresponding | Second Affiliated Hospital of … (CN) | |
| 12 | Quanxin Long Corresponding | Second Affiliated Hospital of … (CN) |
Data: OpenAlex