Basal BNIP3/NIX mitophagy is controlled by selective protect…
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- DOI 10.64898/2026.06.25.734517
- OpenAlex ID W7166153716
- Type Preprint
- Language EN
- Published 26 Jun 2026
- Source bioRxiv (Cold Spring Harbor Laboratory)
- Publisher Cold Spring Harbor Laboratory
- Countries 1
- Institutions 2
- Added 27 Jun 2026
- Updated 28 Oct 2026
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Basal BNIP3/NIX mitophagy is controlled by selective protection of sentinel receptors
Preprint 2026 EN Green
Abstract Mitochondrial homeostasis is maintained by multiple quality control pathways, including mitophagy, which targets dysfunctional mitochondria for degradation. During receptor-mediated mitophagy, the outer membrane proteins BNIP3 and NIX directly recruit autophagy machinery to the mitochondrial surface, though their precise regulation is still unclear. In recent years, new BNIP3- and NIX-int…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
6 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Abhishek Kumar | The University of Texas Southw… (US) | |
| 2 | Abigail C. Love | The University of Texas Southw… (US) | |
| 3 | Keri‐Lyn Kozul | Washington University in St. L… (US) | |
| 4 | Mehmet Oguz Gok | The University of Texas Southw… (US) | |
| 5 | Natalie M. Niemi | Washington University in St. L… (US) | |
| 6 | Jonathan R. Friedman Corresponding | The University of Texas Southw… (US) |
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