A human endometrium-on-chip platform for functional assessment of luminal epithelial receptivity

Successful embryo implantation requires timely acquisition of endometrial receptivity, yet the epithelial mechanisms governing this transition remain poorly understood and difficult to study in humans. Current clinical assessments rely largely on transcriptomic markers, despite limited evidence that these predict functional implantation outcomes. Here, we present a human endometrium-on-chip model…