MetAssist 2.0: A Generalizable Artificial Intelligence Frame…

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MetAssist 2.0: A Generalizable Artificial Intelligence Framework for Lymph Node Metastasis Detection Across Multiple Cancer Types

Article 2026 EN Hybrid

Lymph node metastasis assessment is critical for cancer staging, yet the process is labor intensive and prone to variability, particularly when evaluating micrometastases or isolated tumor cells that can directly alter treatment decisions. We present MetAssist 2.0, a modular artificial intelligence system that combines a pathology foundation model with transformer-based segmentation to automate me…

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14 authors
#AuthorInstitutionsORCID
1 Javier García-Baroja University of Bern (CH)
2 Bastian Dislich University of Bern (CH)
3 Philipp Zens University of Bern (CH)
4 Branislav Zagrapan University of Bern (CH)
5 Fammi Parokkaran University of Bern (CH)
6 Léo Wütschert University of Bern (CH) —
7 Synes Elias Weber University of Bern (CH) —
8 Lucine Christe University of Bern (CH)
9 Christina Neppl Heinrich Heine University Düss… (DE) —
10 Tilman T. Rau Heinrich Heine University Düss… (DE)
11 Aurel A. Perren University of Bern (CH)
12 Yuri Tolkach University Hospital Cologne (DE)
13 Inti Zlobec Corresponding University of Bern (CH)
14 Amjad Khan Corresponding University of Bern (CH)

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