Caspase‐6 Controls Lipid and Energy Metabolism in Diet‐Induc…

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Caspase‐6 Controls Lipid and Energy Metabolism in Diet‐Induced Obesity

Article 2026 EN Gold

Caspases are cysteine proteases that regulate programmed cell death. While caspase-6, an executioner caspase, is known for its role in neurodegeneration and cell death, its broader physiological functions remain poorly understood. Our previous study revealed that caspase-6 drives liver injury and fibrosis in metabolic dysfunction-associate steatohepatitis. Here, we report that caspase-6 deficiency…

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UN Sustainable Development Goals
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8 authors
#AuthorInstitutionsORCID
1 Abhishek Gupta The University of Texas at San… (US) —
2 Wenjing You The University of Texas at San… (US)
3 Linmeng Han The University of Texas at San… (US) —
4 Jianfei Ji The University of Texas at San… (US) —
5 Meixia Pan The University of Texas at San… (US)
6 Xianlin Han The University of Texas at San… (US)
7 Xiaoli Sun Corresponding The University of Texas at San… (US) Mays Cancer Center at UT Healt… (US)
8 Peng Zhao Corresponding The University of Texas at San… (US)

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