Safety and Efficacy of Vinorelbine and Continuous Low‐Dose C…
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- DOI 10.1002/1545-5017.70333
- PMID https://pubmed.ncbi.nlm.nih.gov/41964508
- OpenAlex ID W7153483180
- Type Article
- Language EN
- Published 11 Apr 2026
- Volume 73 (7)
- Pages e70333
- Source Pediatric Blood & Cancer
- Publisher Wiley
- Countries 1
- Institutions 2
- Added 12 Apr 2026
- Updated 31 Oct 2026
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Safety and Efficacy of Vinorelbine and Continuous Low‐Dose Cyclophosphamide Chemotherapy in Japanese Pediatric Patients With Relapsed or Refractory Rhabdomyosarcoma
Article 2026 EN
BACKGROUND: Relapsed or refractory rhabdomyosarcoma (RMS) has a poor prognosis, and optimal treatment remains an unmet need. Vinorelbine (VNR) and low-dose metronomic cyclophosphamide (CPM) have shown clinical efficacy and are used as maintenance therapy in localized and metastatic disease; however, dose reductions are frequently required due to myelosuppression. This study evaluated the safety, e…
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1 SDGsAuthors & Affiliations
10 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Risa Yanai | Jikei University School of Med… (JP) National Cancer Centre Japan (JP) | |
| 2 | Minako Sugiyama | National Cancer Centre Japan (JP) | |
| 3 | Bunpei Miyazaki | National Cancer Centre Japan (JP) | |
| 4 | Natsumi Kikuchi | National Cancer Centre Japan (JP) | — |
| 5 | Kosuke Tamefusa | National Cancer Centre Japan (JP) | |
| 6 | Kayoko Tao | National Cancer Centre Japan (JP) | |
| 7 | Eriko Uchida | National Cancer Centre Japan (JP) | — |
| 8 | Kiyotaka Isobe | National Cancer Centre Japan (JP) | — |
| 9 | Kan Yonemori | Jikei University School of Med… (JP) | |
| 10 | Ayumu Arakawa Corresponding | National Cancer Centre Japan (JP) |
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