Silver‐Catalyzed Radical Addition/Cyclization Cascade Reaction to Access Sulfonylated 4‐Amino‐2‐quinolone Derivatives

We report the synthesis of sulfonylated 4-amino-2-quinolone derivatives from ortho-cyanoarylacrylamides with sodium sulfinates via silver-catalysed radical addition/cyclization cascade reaction. Various substrates were tolerated well and afforded the desired products in good to excellent yields. We have demonstrated a scale-up reaction for this methodology.