New technologies for precise light field microscopy in high-resolution neuroimaging: Automated distortion calibration and correction algorithm

Objective: Light field microscopy (LFM) enables in vivo neuroimaging with high resolution and thus greatly pushes forward biomedical optical imaging research. Although continuous development of optical designs and computational reconstructions, inherent image distortion in LFM systems compromises spatial accuracy and image fidelity, posing a significant barrier to quantitative neuroscience applica…