Antitumor and biological effects of black pine (pinus nigra)…

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  • PMID https://pubmed.ncbi.nlm.nih.gov/18237255
  • OpenAlex ID W52695296
  • Type Article
  • Language EN
  • Published 01 Jan 2008
  • Volume 55 (2)
  • Pages 158–64
  • Source PubMed
  • Publisher National Institutes of Health
  • FWCI 0.83
  • Countries 1
  • Institutions 1
  • Added 24 Jun 2016
  • Updated 12 Oct 2026
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Antitumor and biological effects of black pine (pinus nigra) pollen nuclease.

Article 2008 EN

The antitumor effect of black pine (Pinus nigra) pollen nuclease (PN) tested in vitro was negligible in comparison with bovine seminal ribonuclease (BS-RNase). However, in the experiments in vivo a significant decrease of the human melanoma tumor size was observed in the mice treated with this nuclease and also with the animal RNases and DNase I. In nude mice injected intratumoraly with PN (10 mic…

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7 authors
#AuthorInstitutionsORCID
1 Petra Lipovová University of Chemistry and Te… (CZ)
2 Tomáš Podzimek —
3 Lidmila Orctová — —
4 Jaroslav Matoušek —
5 PAVLA POUCKOVA —
6 J Soucek — —
7 Jaroslav Matoušek —

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