Wharton's jelly mesenchymal stem cell-derived conditioned me…
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- DOI 10.22099/mbrc.2025.52891.2133
- PMID https://pubmed.ncbi.nlm.nih.gov/41346764
- OpenAlex ID W4417076495
- Type Article
- Language EN
- Published 01 Jan 2026
- Volume 15 (1)
- Pages 31–38
- Source Europe PMC (PubMed Central)
- Publisher European Bioinformatics Institute
- FWCI 4.72
- Countries 1
- Institutions 2
- Added 06 Dec 2025
- Updated 27 Oct 2026
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Wharton's jelly mesenchymal stem cell-derived conditioned media inhibits colon cancer cells via activating AMPK/mTOR-mediated autophagy.
Article 2026 EN Green
Prior studies have shown that conditioned media derived from Wharton's jelly mesenchymal stem cells (WJ-CM) have anti-cancer properties. This research investigated the impact of WJ-CM on HT-29 colorectal adenocarcinoma cells by examining autophagy biomarkers and the AMPK/mTOR pathway. The HT-29 cells were subjected to WJ-CM and an AMPK activator (AICAR). Autophagy and levels of AMPK and mTOR prote…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
6 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Dian Dayer | Ahvaz Jundishapur University o… (IR) | |
| 2 | Zahra Akbari Jonoush | Ahvaz Jundishapur University o… (IR) | |
| 3 | Roya Mahdavi | Ahvaz Jundishapur University o… (IR) Birjand University of Medical … (IR) | — |
| 4 | Afshin Amari | Ahvaz Jundishapur University o… (IR) | |
| 5 | Amirhesam Keshavarz | Ahvaz Jundishapur University o… (IR) | |
| 6 | Layasadat Khorsandi | Ahvaz Jundishapur University o… (IR) |
Data: OpenAlex