The effect of progesterone treatment on natural killer cell functional activity and progesterone-induced blocking factor secretion in pregnant women with a history of recurrent pregnancy loss

BACKGROUND: Progesterone is a steroid hormone that plays a crucial role in regulating reproductive processes in women. Its decreased secretion can increase the risk of miscarriage. Progesterone-induced blocking factor is a protein that acts as a mediator of progesterone’s effects. In cases of spontaneous miscarriages, the serum concentration of this protein is lower than during normal pregnancies.…