Comparison of random survival forest and Cox regression for long-term prognosis of pediatric Wilms tumor: based on the SEER database and external validation cohort from China

BACKGROUND: Wilms tumor (WT) is the most common malignant renal tumor in children. Despite advances in treatment, accurate prediction of the long-term prognosis remains challenging. Various Cox regression-based models have been developed to assess WT survival rates; however, there is a pressing need for more precise tools. METHODS: Data from the SEER database (2000-2021) and external validation da…