Multivalent display of VP28 on chimeric virus-like particles…

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Multivalent display of VP28 on chimeric virus-like particles enhances binding to shrimp target tissues: A novel antiviral strategy against white spot syndrome virus

Article 2025 EN Gold

Background and Aim: White spot syndrome virus (WSSV) is a devastating pathogen in shrimp aquaculture, with viral protein 28 (VP28) playing a critical role in host cell attachment and entry. The extracellular domain of VP28 (residues 35–95) is immunogenic and essential for infection; however, its receptor interaction mechanisms remain incompletely elucidated. This study aimed to evaluate the tissue…

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#AuthorInstitutionsORCID
1 Somkid Jaranathummakul Mahidol University (TH) —
2 Pitchanee Jariyapong Walailak University (TH)
3 Orawan Thongsum Mahidol University (TH)
4 Supawich Boonkua Mahidol University (TH)
5 Charoonroj Chotwiwatthanakun Mahidol University (TH)
6 Monsicha Somrit Mahidol University (TH)
7 Somluk Asuvapongpatana Mahidol University (TH)
8 Attaboon Wathammawut Srinakharinwirot University (TH) —
9 Wattana Weerachatyanukul Corresponding Mahidol University (TH)

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