Inhibition of Melanoma Growth by Ex Vivo Expanded Tumor‐Spec…

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Inhibition of Melanoma Growth by Ex Vivo Expanded Tumor‐Specific CD8+ T Cells Is Dependent on the Configuration of Nanoscale Artificial APCs

Article 2025 EN

Adoptive T-cell therapy is an emerging immunotherapeutic strategy for treating cancer, but the compromised quality of CD8+ T-cells limits the therapeutic efficacy. Traditional methods involving polyclonal expansion of CD8+ T-cells mainly prioritize yielding a high quantity of CD8+ T-cells. However, the antigen-specificity of ex vivo expanded CD8+ T-cells and the ability to produce cytolytic molecu…

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8 authors
#AuthorInstitutionsORCID
1 Antara Mondal National Institute of Immunolo… (IN) —
2 Faisal Jamal National Institute of Immunolo… (IN) —
3 Arpita Das National Institute of Immunolo… (IN) —
4 Arnab Kumar Sahoo National Institute of Immunolo… (IN) —
5 Khushboo Chaudhary National Institute of Immunolo… (IN) —
6 Sarmili Chowdhury National Institute of Immunolo… (IN) —
7 Aakriti Jha National Institute of Immunolo… (IN)
8 Santiswarup Singha Corresponding National Institute of Immunolo… (IN)

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