Treatment of pro-B acute lymphoblastic leukemia and severe p…

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Treatment of pro-B acute lymphoblastic leukemia and severe plaque psoriasis with anti-CD19 CAR T cells: a case report

Article 2025 EN Gold

We report on a rare case of adult pro-B acute lymphoblastic leukemia (pro-B ALL) accompanied with severe refractory plaque psoriasis treated using autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. An 18-year-old man with a known history of mild plaque psoriasis for 1 year was diagnosed with pro-B ALL. After induction chemotherapy, his psoriasis began to worsen. Extensive erythem…

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10 authors
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1 Ao Zhang Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1
2 Guangji Zhang Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1 —
3 Huihui Yang Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1
4 Bengfa Gong Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1 —
5 Shouyun Li Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1 —
6 Na Wei Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1
7 Hui Xue Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1 —
8 Hui Wei Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1
9 Jianxiang Wang Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1
10 Shaowei Qiu Corresponding Chinese Academy of Medical Sci… (CN) Institute of Hematology & Bloo… (CN) +1
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