CD19-CAR T-cell therapy induces deep tissue depletion of B c…
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- DOI 10.1136/ard-2024-226142
- PMID https://pubmed.ncbi.nlm.nih.gov/39153835
- OpenAlex ID W4401664751
- Type Article
- Language EN
- Published 17 Aug 2024
- Volume 84 (1)
- Pages 106–114
- Source Annals of the Rheumatic Diseases
- Publisher BMJ
- FWCI 33.15
- Countries 2
- Institutions 6
- Added 18 Aug 2024
- Updated 28 Oct 2026
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CD19-CAR T-cell therapy induces deep tissue depletion of B cells
Article 2024 EN Hybrid
Objectives CD19-targeting chimeric antigen receptor (CAR) T-cell therapy can induce long-term drug-free remission in patients with autoimmune diseases (AIDs). The efficacy of CD19-CAR T-cell therapy is presumably based on deep tissue depletion of B cells; however, such effect has not been proven in humans in vivo. Methods Sequential ultrasound-guided inguinal lymph node biopsies were performed at…
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33.15
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1 SDGsAuthors & Affiliations
23 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Carlo Tur | Università Cattolica del Sacro… (IT) Friedrich-Alexander-Universitä… (DE) +3 | |
| 2 | Markus Eckstein | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) +1 | |
| 3 | Joachim Velden | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | — |
| 4 | Simon Rauber | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 5 | Christina Bergmann | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 6 | Janina Auth | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 7 | Laura Bucci | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | — |
| 8 | Giulia Corte | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 9 | Melanie Hagen | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 10 | Andreas Wirsching | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 11 | Ricardo Grieshaber‐Bouyer | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 12 | Petra Reis | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | — |
| 13 | Nicolai A. Kittan | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | — |
| 14 | Jochen Wacker | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | — |
| 15 | Aleix Rius Rigau | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 16 | Andreas Ramming | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 17 | Maria Antonietta D’Agostino | Università Cattolica del Sacro… (IT) Agostino Gemelli University Po… (IT) +1 | |
| 18 | Arndt Hartmann | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) +1 | — |
| 19 | Fabian Müller | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 20 | Andréas Mackensen | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 21 | Aline Bözec | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) | |
| 22 | Georg Andreas Schett | Università Cattolica del Sacro… (IT) Friedrich-Alexander-Universitä… (DE) +3 | |
| 23 | Maria Gabriella Raimondo Corresponding | Friedrich-Alexander-Universitä… (DE) Universitätsklinikum Erlangen (DE) |
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