Genome Editing for Cystic Fibrosis
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Work Details
- DOI 10.3390/cells12121555
- PMID https://pubmed.ncbi.nlm.nih.gov/37371025
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/10297084
- OpenAlex ID W4379538257
- Type Review
- Language EN
- Published 06 Jun 2023
- Volume 12 (12)
- Pages 1555
- Source Cells
- Publisher Multidisciplinary Digital Publishin…
- FWCI 1.49
- Countries 1
- Institutions 2
- Added 07 Jun 2023
- Updated 29 Oct 2026
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Genome Editing for Cystic Fibrosis
Review 2023 EN Gold
Cystic fibrosis (CF) is a monogenic recessive genetic disorder caused by mutations in the CF Transmembrane-conductance Regulator gene (CFTR). Remarkable progress in basic research has led to the discovery of highly effective CFTR modulators. Now ~90% of CF patients are treatable. However, these modulator therapies are not curative and do not cover the full spectrum of CFTR mutations. Thus, there i…
32
Citations
160
References
1
Authors
1.49
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
1 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Guoshun Wang Corresponding | Louisiana State University (US) Louisiana State University Hea… (US) |
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