A new acid isolated from V. negundo L. inhibits NLRP3 inflam…

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A new acid isolated from V. negundo L. inhibits NLRP3 inflammasome activation and protects against inflammatory diseases

Article 2023 EN Gold

The NLRP3 inflammasome plays a critical role in the innate immune response, and its excessive activation will cause pyroptotic cell death and be associated with the onset of inflammatory diseases. However, NLRP3 inflammasome targeting therapies are still to be implemented in the clinic setting. Here, we first isolated, purified and characterized a novel Vitenegu acid from V. negundo L. herb that s…

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9 authors
#AuthorInstitutionsORCID
1 Qianqian Di Shenzhen University (CN)
2 Xibao Zhao Shenzhen University (CN)
3 Jing Lin Yunnan University (CN)
4 Xunwei Li Shenzhen University (CN) Yunnan University (CN) —
5 Xiaoli Li Shenzhen University (CN) Yunnan University (CN) —
6 Haimei Tang Shenzhen University (CN)
7 Ruihan Zhang Yunnan University (CN)
8 Wei‐Lie Xiao Corresponding Yunnan University (CN)
9 Weilin Chen Corresponding Shenzhen University (CN)

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