Data from Pharmacogenomic Profiling of Pediatric Acute Myelo…

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2023
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  • DOI 10.1158/2643-3230.c.6550904.v1
  • OpenAlex ID W4362547149
  • Type Other
  • Language EN
  • Published 04 Apr 2023
  • Countries 4
  • Institutions 7
  • Added 06 Apr 2023
  • Updated 16 Oct 2026
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Data from Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine

Other 2023 EN Gold

Abstract Despite the expanding portfolio of targeted therapies for adults with acute myeloid leukemia (AML), direct implementation in children is challenging due to inherent differences in underlying genetics. Here we established the pharmacologic profile of pediatric AML by screening myeloblast sensitivity to approved and investigational agents, revealing candidates of immediate clinical relevanc…

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
35 authors
#AuthorInstitutionsORCID
1 Han Wang Chinese University of Hong Kon… (HK)
2 Kathy Yuen Yee Chan Chinese University of Hong Kon… (HK)
3 Chi‐Keung Cheng Chinese University of Hong Kon… (HK)
4 Margaret H.L. Ng Chinese University of Hong Kon… (HK)
5 Po Yi Lee Chinese University of Hong Kon… (HK)
6 Frankie Wai Tsoi Cheng Chinese University of Hong Kon… (HK)
7 Grace Lam Hong Kong Children's Hospital (HK)
8 Tin Wai Chow Hong Kong Children's Hospital (HK)
9 Sy Ha University of Hong Kong (HK)
10 Aks Chiang University of Hong Kong (HK)
11 Wing Hang Leung University of Hong Kong (HK)
12 Anskar Y.H. Leung University of Hong Kong (HK)
13 Chi Chiu Wang Chinese University of Hong Kon… (HK)
14 Tao Zhang Chinese University of Hong Kon… (HK)
15 Xiao‐Bing Zhang Loma Linda University (US)
16 Chi Chiu So Hong Kong Children's Hospital (HK)
17 Yuet Ping Yuen Hong Kong Children's Hospital (HK)
18 Qiwei Sun Chinese University of Hong Kon… (HK)
19 Chi Zhang Chinese University of Hong Kon… (HK)
20 Yaqun Xu Chinese University of Hong Kon… (HK)
21 John Tak Kit Cheung Chinese University of Hong Kon… (HK)
22 Wing Hei Ng Chinese University of Hong Kon… (HK)
23 Patrick Ming‐Kuen Tang —
24 Wei Kang Chinese University of Hong Kon… (HK)
25 Ka‐Fai To Chinese University of Hong Kon… (HK)
26 Wayne Lee Chinese University of Hong Kon… (HK)
27 Raymond S. M. Wong Chinese University of Hong Kon… (HK)
28 Ellen Ngar-Yun Poon Chinese University of Hong Kon… (HK)
29 Qi Zhao University of Macau (MO)
30 Junbin Huang Sun Yat-sen University (CN) The Seventh Affiliated Hospita… (CN)
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