Abstract 96: Integrated molecular analysis of human dediffer…

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  • DOI 10.1158/1538-7445.am2023-96
  • OpenAlex ID W4362542625
  • Type Conference-abstract
  • Language EN
  • Published 04 Apr 2023
  • Volume 83 (7_Supplement)
  • Pages 96
  • Source Cancer Research
  • Publisher American Association for Cancer Res…
  • Countries 1
  • Institutions 1
  • Added 06 Apr 2023
  • Updated 14 Jul 2026
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Abstract 96: Integrated molecular analysis of human dedifferentiated liposarcoma identifies a population of liposarcoma progenitors vulnerable to TGF beta inhibition

Conference-abstract 2023 EN

Abstract Introduction: Dedifferentiated liposarcomas (DDLPS) are the most frequent high-grade soft tissue sarcoma in adults. From a pathological point of view, these tumors are composed of high-grade undifferentiated tumor cells (DD), often showing an abrupt transition from a compartment of well-differentiated adipocytic tumor cells (WD). Tumor cells from both WD and DD compartments are characteri…

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11 authors
#AuthorInstitutionsORCID
1 Nadège Gruel Institut Curie (FR)
2 Chloé Quignot Institut Curie (FR)
3 Julien Vibert Institut Curie (FR)
4 Sylvie Bonvalot Institut Curie (FR)
5 Sophie El Zein Institut Curie (FR)
6 Dimitri Tzanis Institut Curie (FR)
7 Sylvain Baulande Institut Curie (FR)
8 Odette Mariani Institut Curie (FR)
9 Joshua J. Waterfall Institut Curie (FR)
10 Olivier Delattre Institut Curie (FR)
11 Sarah Watson Institut Curie (FR)
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