mTORC1, the master regulator of autophagy

Protein kinase mTORC1 senses a number of intracellular and environmental cues, and targets to different substrates to participate in the regulation of various cellular processes, including cell growth, cell proliferation and cell metabolism. So far, mTORC1 has emerged as a master regulator of autophagy, an important cellular degradation pathway. Multiple proteins, functioning in different stages o…