GC-MS analysis and in silico assessment of constituents of Psidium guajava leaf extract against DNA gyrase of Salmonella enterica serovar Typhi

Typhoid fever is caused by the ingestion of food/water contaminated with Salmonella enterica serovar Typhi (S. Typhi). Treatment of typhoid fever has been by use of antibiotics but it appears the bacterium has mastered the act of resistance against each and every drug targeted at it. Drug discovery in the traditional wet laboratory procedures are cumbersome, costly and slow compared to the rate of…