TLR5 Supports Development of Placental Labyrinthine Zone in …
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- DOI 10.3389/fcell.2021.711253
- PMID https://pubmed.ncbi.nlm.nih.gov/34395439
- OpenAlex ID W3184676298
- Type Article
- Language EN
- Published 28 Jul 2021
- Volume 9
- Pages 711253
- Source Frontiers in Cell and Developmental Biol…
- Publisher Frontiers Media
- FWCI 0.15
- Countries 1
- Institutions 1
- Added 10 Oct 2025
- Updated 19 Oct 2026
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TLR5 Supports Development of Placental Labyrinthine Zone in Mice
Article 2021 EN Gold
Toll plays an important role in innate immunity and embryonic development in lower-ranked animals, but in mammals, the homolog toll-like receptors (TLR) are reported to facilitate postnatal development of immunity only. Here, we discovered a role of TLR5 in placental development. Tlr5 was highly transcribed during the placenta-forming and functional phases. TLR5 deletion led to a smaller placental…
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1 SDGsAuthors & Affiliations
10 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Jensen H. C. Yiu Corresponding | University of Hong Kong (HK) | |
| 2 | Samson W. M. Cheung | University of Hong Kong (HK) | — |
| 3 | Jieling Cai | University of Hong Kong (HK) | — |
| 4 | Kam-Suen Chan | University of Hong Kong (HK) | — |
| 5 | Jing Chen | University of Hong Kong (HK) | — |
| 6 | Lai Yee Cheong | University of Hong Kong (HK) | |
| 7 | Hau-Tak Chau | University of Hong Kong (HK) | |
| 8 | Aimin Xu | University of Hong Kong (HK) | |
| 9 | Raymond Li | University of Hong Kong (HK) | |
| 10 | Connie W. Woo Corresponding | University of Hong Kong (HK) |
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