MK‐STYX Impacts Autophagy and Microtubule Dynamics

Macroautophagy (autophagy) is a critical process that degrades cytoplasmic components to maintain homeostasis and which requires microtubule interactions to function. The autophagosomes (double membrane vesicles) envelop substrates and then are transported along microtubules through motor proteins to fuse with degradative lysosomes. The formation of the autolysosome allows the breakdown and degrad…