Inducibility, but not stability, of atrial fibrillation is i…

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2021
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  • DOI 10.1093/cvr/cvab019
  • PMID https://pubmed.ncbi.nlm.nih.gov/33483749
  • OpenAlex ID W3126104474
  • Type Article
  • Language EN
  • Published 14 Jan 2021
  • Volume 117 (11)
  • Pages 2354–2364
  • Source Cardiovascular Research
  • Publisher Oxford University Press
  • FWCI 4.06
  • Countries 2
  • Institutions 4
  • Added 01 Feb 2021
  • Updated 27 Oct 2026
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Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice

Article 2021 EN Hybrid

AIMS: Gp91-containing NADPH oxidases (NOX2) are a significant source of myocardial superoxide production. An increase in NOX2 activity accompanies atrial fibrillation (AF) induction and electrical remodelling in animal models and predicts incident AF in humans; however, a direct causal role for NOX2 in AF has not been demonstrated. Accordingly, we investigated whether myocardial NOX2 overexpressio…

30

Citations

34

References

11

Authors

4.06

FWCI

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11 authors
#AuthorInstitutionsORCID
1 Alexandra S. Mighiu University of Oxford (GB)
2 Alice Récalde University of Oxford (GB)
3 Klemen Žiberna University of Oxford (GB)
4 Ricardo Carnicer University of Oxford (GB)
5 Jakub Tomek University of Oxford (GB)
6 Gil Bub University of Oxford (GB)
7 Alison C. Brewer King's College London (GB) British Heart Foundation (GB)
8 Sander Verheule Maastricht University (NL)
9 Ajay M. Shah King's College London (GB) British Heart Foundation (GB)
10 Jillian N. Simon Corresponding University of Oxford (GB)
11 Barbara Casadei Corresponding University of Oxford (GB)
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