Interleukin-17 and Interleukin-23: A Narrative Review of Mec…

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Interleukin-17 and Interleukin-23: A Narrative Review of Mechanisms of Action in Psoriasis and Associated Comorbidities

Review 2021 EN Gold

Psoriasis is an immune-mediated inflammatory skin disease associated with numerous inflammatory comorbidities, including increased cardiovascular risk. The interleukin (IL)-23/IL-17 axis plays a central role in the immunopathogenesis of psoriasis and related comorbidities by acting to stimulate keratinocyte hyperproliferation and feed-forwarding circuits of perpetual T cell-mediated inflammation.…

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6 authors
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1 Alan Menter Corresponding Baylor Scott & White Health (US)
2 Gerald G. Krueger University of Utah (US)
3 So Yeon Paek Baylor Scott & White Health (US)
4 Dario Nicolas Kivelevitch Baylor Scott & White Health (US)
5 Iannis E. Adamopoulos University of California, Davi… (US)
6 Richard G B Langley Dalhousie University (CA)

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