Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angioten…
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- DOI 10.1161/atvbaha.120.315322
- PMID https://pubmed.ncbi.nlm.nih.gov/33054395
- OpenAlex ID W3093468392
- Type Article
- Language EN
- Published 15 Oct 2020
- Volume 41 (2)
- Pages 698–710
- Source Arteriosclerosis Thrombosis and Vascular…
- Publisher Lippincott Williams & Wilkins
- FWCI 3.74
- Countries 1
- Institutions 2
- Added 22 Oct 2020
- Updated 27 Oct 2026
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Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)–Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells
Article 2020 EN Hybrid
OBJECTIVE: The superoxide-generating Nox2 (NADPH oxidase-2) is expressed in multiple cell types. Previous studies demonstrated distinct roles for cardiomyocyte, endothelial cell, and leukocyte cell Nox2 in ANG II (angiotensin II)-induced cardiovascular remodeling. However, the in vivo role of fibroblast Nox2 remains unclear. Approach and Results: We developed a novel mouse model with inducible fib…
56
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35
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12
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3.74
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12 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Craig B. Harrison | King's College London (GB) British Heart Foundation (GB) | — |
| 2 | Silvia Cellone Trevelin | King's College London (GB) British Heart Foundation (GB) | |
| 3 | Daniel A. Richards | King's College London (GB) British Heart Foundation (GB) | |
| 4 | Célio X.C. Santos | King's College London (GB) British Heart Foundation (GB) | — |
| 5 | Greta Jane Sawyer | King's College London (GB) British Heart Foundation (GB) | |
| 6 | Andrea Markovinović | King's College London (GB) | |
| 7 | Xiaohong Zhang | King's College London (GB) British Heart Foundation (GB) | |
| 8 | Min Zhang | King's College London (GB) British Heart Foundation (GB) | |
| 9 | Alison C. Brewer | King's College London (GB) British Heart Foundation (GB) | |
| 10 | Xiaoke Yin | King's College London (GB) British Heart Foundation (GB) | |
| 11 | Manuel Mayr | King's College London (GB) British Heart Foundation (GB) | |
| 12 | Ajay M. Shah | King's College London (GB) British Heart Foundation (GB) |
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