The DNA methylome of human sperm is distinct from blood with…
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- DOI 10.1371/journal.pgen.1009035
- PMID https://pubmed.ncbi.nlm.nih.gov/33048947
- OpenAlex ID W3092304831
- Type Article
- Language EN
- Published 13 Oct 2020
- Volume 16 (10)
- Pages e1009035
- Source PLoS Genetics
- Publisher Public Library of Science
- FWCI 1.04
- Countries 1
- Institutions 8
- Added 15 Oct 2020
- Updated 27 Oct 2026
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The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations
Article 2020 EN Gold
Epidemiological research suggests that paternal obesity may increase the risk of fathering small for gestational age offspring. Studies in non-human mammals indicate that such associations could be mediated by DNA methylation changes in spermatozoa that influence offspring development in utero. Human obesity is associated with differential DNA methylation in peripheral blood. It is unclear, howeve…
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10
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1.04
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10 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Fredrika Åsenius | University College London (GB) | |
| 2 | T.J. Gorrie-Stone | University of Essex (GB) | |
| 3 | Ama Brew | Queen Mary University of Londo… (GB) Blizard Institute (GB) | |
| 4 | Yasmin Panchbhaya | University College London (GB) | — |
| 5 | Elizabeth Williamson | University College Hospital (GB) | — |
| 6 | Leonard C. Schalkwyk | University of Essex (GB) | |
| 7 | Vardhman K. Rakyan | Queen Mary University of Londo… (GB) Blizard Institute (GB) | |
| 8 | Michelle L. Holland | King's College London (GB) | |
| 9 | Sarah J. Marzi Corresponding | UK Dementia Research Institute (GB) Imperial College London (GB) | |
| 10 | David J. Williams | University College London (GB) |
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