Identification of Novel Potential Type 2 Diabetes Genes Medi…

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Identification of Novel Potential Type 2 Diabetes Genes Mediating β-Cell Loss and Hyperglycemia Using Positional Cloning

Article 2020 EN Gold

Type 2 diabetes (T2D) is a complex metabolic disease regulated by an interaction of genetic predisposition and environmental factors. To understand the genetic contribution in the development of diabetes, mice varying in their disease susceptibility were crossed with the obese and diabetes-prone New Zealand Obese (NZO) mouse. Subsequent whole-genome sequence scans revealed one major QTL, Nidd/DBA…

8

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45

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16

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1.14

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16 authors
#AuthorInstitutionsORCID
1 Heja Aga German Center for Diabetes Res… (DE) German Institute of Human Nutr… (DE)
2 Nicole Hallahan German Center for Diabetes Res… (DE) German Institute of Human Nutr… (DE)
3 Pascal Gottmann German Center for Diabetes Res… (DE) German Institute of Human Nutr… (DE)
4 Markus Jähnert German Center for Diabetes Res… (DE) German Institute of Human Nutr… (DE)
5 Sophie Osburg German Center for Diabetes Res… (DE) German Institute of Human Nutr… (DE) —
6 Gunnar Schulze German Center for Diabetes Res… (DE) German Institute of Human Nutr… (DE) —
7 Anne Kamitz German Center for Diabetes Res… (DE) German Institute of Human Nutr… (DE) —
8 Danny Arends Humboldt-Universität zu Berlin (DE)
9 Gudrun A. Brockmann Humboldt-Universität zu Berlin (DE)
10 Tanja Schallschmidt Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 —
11 Sandra Lebek Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1 —
12 Alexandra Chadt Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1
13 Hadi Al‐Hasani Deutsches Diabetes-Zentrum e.V… (DE) German Center for Diabetes Res… (DE) +1
14 Hans‐Georg Joost German Center for Diabetes Res… (DE) German Institute of Human Nutr… (DE)
15 Annette Schürmann University of Potsdam (DE) German Center for Diabetes Res… (DE) +1
16 Heike Vogel Corresponding University of Potsdam (DE) German Center for Diabetes Res… (DE) +1

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