The NADPH Oxidase Isoform 1 Contributes to Angiotensin II-Me…

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2020
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  • DOI 10.3390/antiox9070586
  • PMID https://pubmed.ncbi.nlm.nih.gov/32635630
  • OpenAlex ID W3038303048
  • Type Article
  • Language EN
  • Published 05 Jul 2020
  • Volume 9 (7)
  • Pages 586
  • Source Antioxidants
  • Publisher Multidisciplinary Digital Publishin…
  • FWCI 1.12
  • Countries 1
  • Institutions 2
  • Added 10 Oct 2025
  • Updated 12 Oct 2026
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The NADPH Oxidase Isoform 1 Contributes to Angiotensin II-Mediated DNA Damage in the Kidney

Article 2020 EN Gold

In higher concentrations, the blood pressure regulating hormone angiotensin II leads to vasoconstriction, hypertension, and oxidative stress by activating NADPH oxidases which are a major enzymatic source of reactive oxygen species (ROS). With the help of knockout animals, the impact of the three predominant NADPH oxidases present in the kidney, i.e., Nox1, Nox2 and Nox4 on angiotensin II-induced…

15

Citations

44

References

5

Authors

1.12

FWCI

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
5 authors
#AuthorInstitutionsORCID
1 Anna Zimnol Heinrich Heine University Düss… (DE) —
2 Nora Spicker Heinrich Heine University Düss… (DE) —
3 Ronja Balhorn Heinrich Heine University Düss… (DE) —
4 Katrin Schröder Goethe University Frankfurt (DE)
5 Nicole Schupp Corresponding Heinrich Heine University Düss… (DE)

Data: OpenAlex