The study of the role of macrophage and macrophage autophagy in atherosclerosis

Atherosclerosis (AS) is a chronic vascular disorder, leading to a variety of cardiovascular and cerebrovascular diseases. So far, we attribute it to abnormal lipid metabolism and dysregulation of immune response induced by excessive cholesterol accumulation in macrophages. In this review, we conclude recent researches on the function of macrophages and autophagy in AS, and summarize macrophage rel…