Abstract 1995: PTHrP drives tumor initiation signaling pathw…

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  • DOI 10.1158/1538-7445.am2018-1995
  • OpenAlex ID W2885257451
  • Type Conference-abstract
  • Language EN
  • Published 01 Jul 2018
  • Volume 78 (13_Supplement)
  • Pages 1995
  • Source Cancer Research
  • Publisher American Association for Cancer Res…
  • Countries 1
  • Institutions 3
  • Added 22 Aug 2018
  • Updated 13 Oct 2026
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Abstract 1995: PTHrP drives tumor initiation signaling pathways in the PyMT model of breast cancer progression

Conference-abstract 2018 EN

Abstract Parathyroid hormone-related peptide (PTHrP) was first discovered in cancer patients as the primary cause of malignancy associated hypercalcemia (MAH) & is overexpressed in most human breast tumors. We previously showed that PTHrP ablation, in the MMTV-PyMT murine model of breast cancer progression can dramatically prolong tumor latency, slows tumor growth & metastases. Here we examined th…

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
6 authors
#AuthorInstitutionsORCID
1 Rui Zhang McGill University Health Centr… (CA) McGill University (CA)
2 Jiarong Li McGill University Health Centr… (CA) McGill University (CA)
3 Dunarel Badescu McGill University (CA) —
4 Andrew C. Karaplis Lady Davis Institute for Medic… (CA)
5 Jiannis Ragoussis McGill University (CA)
6 Richard B. Kremer McGill University Health Centr… (CA) McGill University (CA)

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