Streptococcus mutans activates the AIM2, NLRP3 and NLRC4 inf…

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Streptococcus mutans activates the AIM2, NLRP3 and NLRC4 inflammasomes in human THP-1 macrophages

Article 2018 EN Gold

Streptococcus mutans (S. mutans), a major aetiologic agent of dental caries, is involved in systemic diseases, such as bacterial endocarditis, if it enters the bloodstream through temporary bacteraemia. Interleukin (IL)-1β, a proinflammatory cytokine, is related to the host defences against pathogens, and its synthesis, maturation, and secretion are tightly regulated by the activation of the infla…

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6 authors
#AuthorInstitutionsORCID
1 Yuri Song Pusan National University Dent… (KR) Pusan National University (KR)
2 Hee Sam Na Pusan National University Dent… (KR) Pusan National University (KR)
3 Eun-Joo Park Pusan National University Dent… (KR) Pusan National University (KR)
4 Mi Hee Park Pusan National University Dent… (KR) Pusan National University (KR)
5 Hyun Ah Lee Pusan National University Dent… (KR) Pusan National University (KR)
6 Jin Chung Corresponding Pusan National University Dent… (KR) Pusan National University (KR)

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