Lectin-mediated binding and sialoglycans of porcine surfacta…
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- DOI 10.1074/jbc.ra117.001430
- PMID https://pubmed.ncbi.nlm.nih.gov/29769321
- OpenAlex ID W2803533771
- Type Article
- Language EN
- Published 16 May 2018
- Volume 293 (27)
- Pages 10646–10662
- Source Journal of Biological Chemistry
- Publisher Elsevier BV
- FWCI 1.15
- Countries 2
- Institutions 4
- Added 01 Jun 2018
- Updated 27 Oct 2026
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Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus
Article 2018 EN Hybrid
Innate immunity is critical in the early containment of influenza A virus (IAV) infection, and surfactant protein D (SP-D) plays a crucial role in the pulmonary defense against IAV. In pigs, which are important intermediate hosts during the generation of pandemic IAVs, SP-D uses its unique carbohydrate recognition domain (CRD) to interact with IAV. An N -linked CRD glycosylation provides interacti…
21
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55
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12
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1.15
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1 SDGsAuthors & Affiliations
12 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Martin van Eijk Corresponding | Utrecht University (NL) | — |
| 2 | Michael J. Rynkiewicz | Boston University (US) | |
| 3 | Kshitij Khatri | Boston University (US) | |
| 4 | Nancy Leymarie | Boston University (US) | — |
| 5 | Joseph Zaia | Boston University (US) | |
| 6 | Mitchell R. White | Boston University (US) | |
| 7 | Kevan L. Hartshorn | Boston University (US) | |
| 8 | Tanya M. Cafarella | Boston University (US) | — |
| 9 | Irma van Die | Amsterdam UMC Location Vrije U… (NL) | |
| 10 | Martin Hessing | University Medical Center Utre… (NL) | — |
| 11 | Barbara A. Seaton | Boston University (US) | |
| 12 | Henk P. Haagsman | Utrecht University (NL) |
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