The serotonin producing enterochromaffin cell, and effects of hyperserotoninemia on heart and bone.

Neuroendocrine (NE) cells are found in a majority of the body organs. In the gastrointestinal (GI) tract, enterochromaffin cells (EC) constitute the largest NE cell population and they are distributed from the cardia to the anus. The EC cell population includes several different sub-populations, and morphological differences in shape, luminal endings and secretory granules suggest region-specific…