Screening of medicinal plants of Himachal Pradesh for efflux pump inhibitory activity against Escherichia coli

Rapid increase of multidrug resistance in bacteria has made the discovery of new antimicrobials necessary. From the time of discovery of bacterial efflux pumps in 1980, many bacteria have been characterized as multi drug resistant. Efflux pumps expel out the antibiotics and other resistance modifying compounds and dyes. Antibiotic resistance developed very quickly due to the changes in expression…