Tocilizumab (Anti-IL-6R) Suppressed TNFα Production by Human…

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DOI 10.1097/txd.0000000000000653
PMID https://pubmed.ncbi.nlm.nih.gov/28361123
PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/5367756
OpenAlex ID W2588649078
Type Article
Language EN
Published 16 Feb 2017
Volume 3 (3)
Pages e139
Source Transplantation Direct
Publisher Wolters Kluwer
FWCI 0.87
Countries 1
Institutions 2
Added 24 Feb 2017
Updated 28 Oct 2026

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Tocilizumab (Anti-IL-6R) Suppressed TNFα Production by Human Monocytes in an In Vitro Model of Anti-HLA Antibody-Induced Antibody-Dependent Cellular Cytotoxicity

Article 2017 EN Gold

BACKGROUND: We previously demonstrated that natural killer (NK) cells activated via FcγRIIIa (CD16) interactions with anti-HLA antibodies binding to peripheral blood mononuclear cells (PBMCs) in the in vitro antibody-dependent cellular cytotoxicity (ADCC) assay produced IFNγ. Here we investigate if other CD16 bearing cells are responsive to alloantigen via alloantibody in the in vitro ADCC and if…

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5 authors

#	Author	Institutions	ORCID
1	Bongha Shin Corresponding	Cedars-Sinai Medical Center (US) University of California, Los … (US)
2	Shili Ge	Cedars-Sinai Medical Center (US) University of California, Los … (US)	—
3	James Mirocha	Cedars-Sinai Medical Center (US) University of California, Los … (US)
4	Stanley C. Jordan	Cedars-Sinai Medical Center (US) University of California, Los … (US)
5	Mieko Toyoda	Cedars-Sinai Medical Center (US) University of California, Los … (US)

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