The effect of hypoxia on free and encapsulated adult porcine…
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- DOI 10.1111/xen.12275
- PMID https://pubmed.ncbi.nlm.nih.gov/28247506
- OpenAlex ID W2548367613
- Type Article
- Language EN
- Published 05 Nov 2016
- Volume 24 (1)
- Source Xenotransplantation
- Publisher Wiley
- FWCI 2.67
- Countries 1
- Institutions 3
- Added 10 Oct 2025
- Updated 22 Sep 2026
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The effect of hypoxia on free and encapsulated adult porcine islets—an in vitro study
Article 2016 EN Green
BACKGROUND: Adult porcine islets (APIs) constitute a promising alternative to human islets in treating type 1 diabetes. The intrahepatic site has been used in preclinical primate studies of API xenografts; however, an estimated two-thirds of donor islets are destroyed after intraportal infusion due to a number of factors, including the instant blood-mediated inflammatory reaction (IBMIR), immunosu…
26
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41
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6
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2.67
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
6 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Sudhakar Muthyala | Georgia Institute of Technolog… (US) | — |
| 2 | Susan A. Safley | Emory University (US) | |
| 3 | Kereen Gordan | Emory University (US) | — |
| 4 | Graham F. Barber | Emory University (US) | — |
| 5 | Collin Joel Weber | Emory University (US) | |
| 6 | Athanassios Sambanis Corresponding | Georgia Institute of Technolog… (US) W. M. Keck Foundation (US) |
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