Liquid chromatographic separation of enantiomeric drugs.

Enantiomers of many drugs show differences in pharmacological activities and in metabolisms. Since such drugs are often used as racemic mixtures, it is important to determine the amounts of each enantiomer in biological fluids in order to optimize therapy and to avoid undesirable side effects. Recently, chromatographic methods have been developed for the separation of enantiomeric compounds. In pr…