New pharmacological studies with pentoxifylline

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New pharmacological studies with pentoxifylline

Article 1990 EN

Polymorphonuclear (PMN) overactivation plays a critical role in microcirculation as well as in conditions such as multiorgan failure (MOF). Pentoxifylline has been shown to prevent PMN activation by endotoxin and cytokines such as TNF alpha and IL-1. In addition, MOF induced by IL-2 in animals can be prevented by pentoxifylline. The present studies evaluated two aspects of PMN activation and pento…

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3 authors
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1 William J. Novick — —
2 Gail W. Sullivan University of Virginia (US) —
3 Gerald L. Mandell University of Virginia (US) —

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