Differential effects of putative protein kinase C inhibitors…

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Differential effects of putative protein kinase C inhibitors on contraction of rat aortic smooth muscle

Article 1993 EN

We investigated effects of three kinds of putative protein kinase C (PKC) inhibitors, calphostin C, 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7), and stauro-sporine, on aortic muscle contractions induced by KCl, phenylephrine, 12-O-tetradecanoylphorbol-13-acetate (TPA), and phorbol 12, 13-dibutyrate (PDBu). Calphostin C noncompetitively inhibited TPA-induced contractions in a concentration-…

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4 authors
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1 Yoriko Shimamoto McMaster University (CA) —
2 H Shimamoto McMaster University (CA) —
3 C.Y. Kwan McMaster University (CA) —
4 Edwin E. Daniel McMaster University (CA) —

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